1) Change all of the following values located in section <configSections> --> <sectionGroup name="system.webServer">

<section name="handlers" overrideModeDefault="Deny" /> <--- change this value from "Deny" to "Allow"
<section name="modules" allowDefinition="MachineToApplication" overrideModeDefault="Deny" /> <--- change this value from "Deny" to "Allow"

2) Simply register asp.net with IIS.

Go to the VS command prompt and run this:

aspnet_regiis.exe -i

3) iekš IIS managera konkrēto web projekta mapi konvertējam uz aplikāciju:
MRB -> Convert to Application